Progress in the study on peptide synthesis catalyzed by immobilized enzyme

The review deals with the factors which have influence on peptide synthesis catalyzed by immobilized enzyme and its application for peptide synthesis. Particular attention is paid to important effect factors, such as solvent, support, pH value, etc. and the reasons for these effects are discussed. I mmobilized enzymes applied to peptide synthesis, i.e., sweetener aspartame, enkephalin and other bioactive peptides and so on, were briefly summarized .