Protein stability: The COP9 signalosome gets in on the act

Citation
M. Seeger et al., Protein stability: The COP9 signalosome gets in on the act, CURR BIOL, 11(16), 2001, pp. R643-R646
Citations number
25
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
11
Issue
16
Year of publication
2001
Pages
R643 - R646
Database
ISI
SICI code
0960-9822(20010821)11:16<R643:PSTCSG>2.0.ZU;2-M
Abstract
The COP9 signalosome is a multiprotein complex somewhat similar to the lid component of the 26S proteasome. Recent studies suggest that it regulates t he stability of proteins by interfering with the ubiquitin-proteasome pathw ay via deneddylation and phosphorylation.