Remobilizing P elements out of the stambh A locus of Drosophila melanogaster

Citation
Mp. Rao et al., Remobilizing P elements out of the stambh A locus of Drosophila melanogaster, CURRENT SCI, 81(3), 2001, pp. 311-314
Citations number
11
Categorie Soggetti
Multidisciplinary,Multidisciplinary
Journal title
CURRENT SCIENCE
ISSN journal
00113891 → ACNP
Volume
81
Issue
3
Year of publication
2001
Pages
311 - 314
Database
ISI
SICI code
0011-3891(20010810)81:3<311:RPEOOT>2.0.ZU;2-M
Abstract
P elements from two P-tagged alleles, stm A(P1) and stm A(P4), of the tempe rature-sensitive paralytic mutant stambh A (stm A) were remobilized to deri ve wild-type revertants and P excision lethals. stm Apt remutated to lethal ity, while stm A(P4) reverted to the wild type. The P excision lethals are not amorphic mutations, since they were weaker in paralytic phenotype (i) t han the parental P-tagged allele and (ii) for deficiencies for stm A. The l ethals collectively affected all stages of the life cycle, demonstrating th at stm A(+) is needed throughout fly development.