Cutaneous necrobiotic xanthogranuloma (NXG) - successfully treated with low dose chlorambucil

Authors
Machado, S Alves, R Lima, M Leal, I Massa, A
Citation
S. Machado et al., Cutaneous necrobiotic xanthogranuloma (NXG) - successfully treated with low dose chlorambucil, EUR J DERM, 11(5), 2001, pp. 458-462
Citations number
22
Categorie Soggetti
da verificare
Journal title
EUROPEAN JOURNAL OF DERMATOLOGY
ISSN journal
11671122 → ACNP
Volume
11
Issue
5
Year of publication
2001
Pages
458 - 462
Database
ISI
SICI code
1167-1122(200109/10)11:5<458:CNX(-S>2.0.ZU;2-2
Abstract
We, report a case of necrobiotic xanthogranuloma in a 51 year-old white mal e patient presenting with a 6-year history of multiple indurated violaceous nodules and plaques involving the eyelids, trunk and extremities. He had a n associated paraproteinemia (Ig G lambda), elevated sedimentation rate, cr yoglobulinemia and hypocomplementemia. No extracutaneous involvement was de tected. He was successfully treated with chlorambucil (2 mg/d for 7 months) , leading to disappearance of all skin lesions.