Neurokinin B. a peptide belonging to the tachykinin family, is undetectable
in peripheral tissues from nonpregnant animals. In the present study, we a
nalysed the expression of the preprotachykinia-B (PPT-B) gene, which encode
s neurokinin B, in the rat uterus. Preprotachykinin-B mRNA was expressed in
the uterus and its levels varied greatly depending upon the hormonal condi
tions. This is consistent with a role of this tachykinin in the regulation
of uterine functions. (C) 2001 Elsevier Science B.V. All rights reserved.