Objectives: to investigate the prevalence of MRSA infection in patients tre
ated in a major vascular unit and examine its consequences.
Design and Methods: a retrospective case-note review was performed.
Results: during the period 1993 to 2000, a total of 172 patients (4.4% of t
otal) were positive for MRSA. Of these 97 were colonised and 75 were infect
ed by MRSA. The proportion of wound or graft infections caused by MRSA has
increased (4% in 1994 to 63% in 2000). Three patients developed native arte
ry infection (one following aortic stent insertion and 2 following embolect
omy). All patients with aortic graft infection died. All patients with infe
cted prosthetic infrainguinal bypass ended up with an amputation.
Conclusion: the prevalence of MRSA infection is increasing. Infection of ao
rtic grafts appears to be uniformly fatal and lower limb graft infection is
associated with high limb loss.