Background. The risk of people with Parkinson's disease (PD) failing is gre
ater than that of the general population but to date, disease-specific pred
ictors of failing have not been identified. Objectives: To identify one or
more features, which would predict individuals at risk of falling during a
3-month prospective follow-up study. Method: A battery of standardised test
s administered in the home and the laboratory with a 3-month follow-up tele
phone interview. Results: Sixty-three people with PD were recruited from GP
practices. Eleven interview variables and six gait laboratory variables we
re used with subsamples (55 and 44 subjects, respectively) to fit predictiv
e models for identifying future fallers. The number of falls in the previou
s year was the most important variable, without exception, to be selected a
s a predictor in various logistic regression models. A history of two or mo
re falls had a sensitivity of 86.4% (95% Cl 67.3-96.2%) and a specificity o
f 85.7% (95% Cl 71.2-94.2%) in predicting falling in the next 3 months. Con
clusion: Healthcare workers should be asking their patients with PD regular
ly and carefully about falling, and should consider instigating programmes
of fall management for patients with PD who have fallen two or more times i
n the previous 12 months. Copyright (C) 2001 S. Karger AG, Basel.