Proteomics reveals open reading frames in Mycobacterium tuberculosis H37Rvnot predicted by genomics

Authors
Jungblut, PR Muller, EC Mattow, J Kaufmann, SHE
Citation
Pr. Jungblut et al., Proteomics reveals open reading frames in Mycobacterium tuberculosis H37Rvnot predicted by genomics, INFEC IMMUN, 69(9), 2001, pp. 5905-5907
Citations number
11
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
69
Issue
9
Year of publication
2001
Pages
5905 - 5907
Database
ISI
SICI code
0019-9567(200109)69:9<5905:PRORFI>2.0.ZU;2-M
Abstract
Genomics revealed the sequence of 3924 genes of the H37Rv strain of Mycobac terium tuberculosis. Proteomics complements genomics in showing which genes are really expressed, and here we show the expression of six genes not pre dicted by genomics, as proved by two-dimensional electrophoresis and matrix -assisted laser desorption ionization and nano-electrospray mass spectromet ry.