Cryptosporidium parvum infection requires host cell actin polymerization

Authors
Elliott, DA Coleman, DJ Lane, MA May, RC Machesky, LM Clark, DP
Citation
Da. Elliott et al., Cryptosporidium parvum infection requires host cell actin polymerization, INFEC IMMUN, 69(9), 2001, pp. 5940-5942
Citations number
32
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
69
Issue
9
Year of publication
2001
Pages
5940 - 5942
Database
ISI
SICI code
0019-9567(200109)69:9<5940:CPIRHC>2.0.ZU;2-J
Abstract
The intracellular protozoan parasite Cryptosporidium parvum accumulates hos t cell actin at the interface between the parasite and the host cell cytopl asm. Here we show that the actin polymerizing proteins Arp2/3, vasodilator- stimulated phosphoprotein (VASP), and neural Wiskott Aldrich syndrome prote in (N-WASP) are present at this interface and that host cell actin polymeri zation is necessary for parasite infection.