Determination of 4,4 '-dinitrocarbanilide (DNC), the active component of the antifertility agent nicarbazin, in chicken, duck, and goose plasma

Authors
Primus, TM Kohler, DJ Goodall, MA Yoder, C Griffin, D Miller, L Johnston, JJ
Citation
Tm. Primus et al., Determination of 4,4 '-dinitrocarbanilide (DNC), the active component of the antifertility agent nicarbazin, in chicken, duck, and goose plasma, J AGR FOOD, 49(8), 2001, pp. 3589-3593
Citations number
12
Categorie Soggetti
Agricultural Chemistry","Chemistry & Analysis
Journal title
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
ISSN journal
00218561 → ACNP
Volume
49
Issue
8
Year of publication
2001
Pages
3589 - 3593
Database
ISI
SICI code
0021-8561(200108)49:8<3589:DO4'(T>2.0.ZU;2-S
Abstract
4,4 ' -Dinitrocarbanilide (DNC) was extracted from chicken, duck, and goose plasma and isolated by reversed-phase high-performance liquid chromatograp hy. DNC was detected by ultraviolet absorbance at 347 nm and quantified by comparison to a calibration standard. Recovery data were determined by anal yzing DNC-fortified control plasma. The mean recovery of DNC in fortified c hicken plasma samples was 99.7 +/- 1.9% for 0.18 and 9.1 ppm DNC, and in fo rtified duck and goose plasma samples was 99.5 +/- 4.9% and 101.4 +/- 4.5%, respectively, for 0.18, 9.1, and 18 ppm DNC.