Does sperm morphology play a significant role in increased sex chromosomaldisomy? A comparison between patients with teratozoospermia and OAT by FISH

Authors
Gole, LA Wong, PF Ng, PL Wang, XQ Ng, SC Bongso, A
Citation
La. Gole et al., Does sperm morphology play a significant role in increased sex chromosomaldisomy? A comparison between patients with teratozoospermia and OAT by FISH, J ANDROLOGY, 22(5), 2001, pp. 759-763
Citations number
24
Categorie Soggetti
da verificare
Journal title
JOURNAL OF ANDROLOGY
ISSN journal
01963635 → ACNP
Volume
22
Issue
5
Year of publication
2001
Pages
759 - 763
Database
ISI
SICI code
0196-3635(200109/10)22:5<759:DSMPAS>2.0.ZU;2-G
Abstract
Eight semen samples from men with teratozoospermia (T), along with samples from 3 men with normal fertility and 5 samples from men with oligoasthenote ratozoospermia (OAT) were analyzed for X and Y chromosomal anomalies with t he use of fluorescently labeled centromeric probes. This study was undertak en to determine whether patients with abnormal sperm morphology (teratozoos permia) have increased or decreased incidence of a sex chromosomal anomaly. The sex chromosome disomy for the T samples was 0.36% and for the OAT grou p it was 0.61%, compared with baseline value for the normozoospermia group (0.09%).