Endosonographic images of low-grade lymphoma of mucosa-associated lymphoidtissue after radiotherapy

Recently, radiation therapy has been reported to be effective in patients w ith low-grade lymphoma of mucosa-associated lymphoid tissue (MALT) of the s tomach. We describe changes in endoscopic ultrasonographic (EUS) findings a fter radiation therapy in a patient with low-grade gastric MALT lymphoma. E ndoscopic ultrasonography initially showed enlargement of regional lymph no des and diffuse thickening of the second and third mural layers in the gast ric body. Two months after the end of radiation therapy, EUS showed hypoech oic changes in the third layer that corresponded to the ulcer scar but no w all thickening or lymph node enlargement. The hypoechoic changes were thoug ht to reflect inflammatory change. We conclude that EUS is useful for asses sing the response to radiation therapy in patients with low-grade gastric M ALT lymphoma.