G. Heinisch et al., Pyridazines 93. An unexpected reaction behaviour of 3-aminopyridazine towards 2-methylphenylisocyanate, J HETERO CH, 38(4), 2001, pp. 945-948
Reaction of 3-aminopyridazine (1) with 2-methylphenylisocyante (4) affords
not only the desired urea derivative (5) but also an unexpected side-produc
t (6), which could be identified as the corresponding biuret derivative by
means of elemental and spectroscopic data as well as crystal structure dete
rmination.