Synthesis of bis-heteroaryl piperazine derivatives as potential reverse transcriptase inhibitors

Authors
Guillaumel, J Grierson, DS Monneret, C
Citation
J. Guillaumel et al., Synthesis of bis-heteroaryl piperazine derivatives as potential reverse transcriptase inhibitors, J HETERO CH, 38(4), 2001, pp. 985-988
Citations number
21
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
38
Issue
4
Year of publication
2001
Pages
985 - 988
Database
ISI
SICI code
0022-152X(200107/08)38:4<985:SOBPDA>2.0.ZU;2-O
Abstract
Vinylogous analogs of non-nucleoside reverse transcriptase inhibitors belon ging to the bis-(heteroaryl)piperazine (BHAP) series were synthesized by co upling a piperazine derivative with (E)-propenoyl derivatives of heterocycl ic moieties.