Acanthoparyphium tyosenense Yamaguti, 1939 (Digenca: Echinostomatidae), was
originally reported as an avian intestinal parasite. here, its presence is
reported in 10 humans in the Republic of Korea. The patients were 9 adults
aged 35-66 yr (males and females) and a young girl aged 7 yr residing in 2
coastal villages in Puan-gun, Chollabuk-do. The worms were recovered after
treatment with praziquantel and purgation with magnesium salts. A total of
158 specimens (1-107 specimens/ individual) was collected, together with v
arying numbers of other intestinal flukes. The patients had eaten various k
inds of brackish water mollusks caught in an estuary near their villages. F
ive bivalves and a gastropod species suspected as sources of human infectio
n were collected and examined. Two bivalves (Mactra veneriformis and Solen
grandis) and the gastropod (Neverita bicolor) were found to be infected wit
h the metacercariae of A. tyosenense; adult flukes were confirmed after the
experimental infection of chicks. The results show that A. tyosenense infe
cts humans and that brackish water mollusks are the source of human infecti
on.