Application of reinecke salt and alizarin S for the determination of promazine

Reinecke salt and alizarin S have been tested as reagents for the determina tion of promazine. They react in neutral and acidic media with promazine fo rming a reddish and brown crystalline compounds. The compounds are sparingl y soluble in water but fairly soluble in acetone and methanol. The quantita tive extraction of compound of promazine with alizarin S has been used for the extractive spectrophotometric determination of promazine. Formation of promazine ion-association complex with Reinecke salt has been applied for i ndirect determination of low concentrations of promazine by AAS measurement of the chromium content of the reineckate counter - anion. (C) 2001 Elsevi er Science B.V. All rights reserved.