A new approach to the synthesis of (+/-)-methyl jasmonate and (+/-)-baclofen via conjugated addition of oxazoline cyanocuprate to Michael acceptors.

Authors
dos Santos, AA Clososki, GC Simonelli, F de Oliveira, ARM Marques, FD Zarbin, PHG
Citation
Aa. Dos Santos et al., A new approach to the synthesis of (+/-)-methyl jasmonate and (+/-)-baclofen via conjugated addition of oxazoline cyanocuprate to Michael acceptors., J BRAZ CHEM, 12(5), 2001, pp. 673-679
Citations number
38
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
ISSN journal
01035053 → ACNP
Volume
12
Issue
5
Year of publication
2001
Pages
673 - 679
Database
ISI
SICI code
0103-5053(200107/08)12:5<673:ANATTS>2.0.ZU;2-B
Abstract
Introduction of a synthon equivalent to a carboxymethyl anion to enones and nitroalkenes, through a 1,4- addition reaction of 2,4,4-trimethyl-2-oxazol ine cyanocuprate 3, proved to be an interesting methodology for the synthes is of natural products such as (+/-)-methyl jasmonate (1) and (+/-)-baclofe n (2).