Epidemiology: Since both migraine and vertigo are common complaints in clin
ical practice they may coincide in an individual patient just by chalice. T
here are, however, numerous patients with vestibular symptoms caused by mig
raine, accounting for 6-8% of diagnoses in specialized dizziness clinics.
Clinical Manifestation: Migraine-associated vertigo is a vestibular disorde
r which manifests itself with spontaneous or positional rotational vertigo
or dizziness induced by head motion. The vertigo may occur without accompan
ying headache and may last from seconds to several weeks.
Diagnosis: Migraine-associated vertigo can be diagnosed according to the fo
llowing criteria: 1. recurrent vestibular symptoms, 2. migraine according t
o the criteria of the International Headache Society, 3. migrainous symptom
s during the vertigo such as headache, photophobia, phonophobia, scintillat
ing scotoma or other auras, 4. exclusion of other causes.
Pathophysiology: The mechanism of migraine-associated vertigo is still obsc
ure. Several hypotheses relating to the pathophysiology of migraine have be
en proposed: cortical spreading depression, regional changes in brain perfu
sion, release of neurotransmitters and paroxysmal dysfunction of ion channe
ls. Clinical findings suggest both central and peripheral vestibular involv
ement.
Therapy: Treatment is based on the repertoire of acute and prophylactic med
ications that are used for migrainous headaches. Controlled studies on the
treatment of migraine-associated vertigo are still lacking.