Ral. Macdonell et al., Prolonged cortical silent period after transcranial magnetic stimulation in generalized epilepsy, NEUROLOGY, 57(4), 2001, pp. 706-708
Transcranial magnetic stimulation (TMS) produces a cortical silent period (
CSP) during a voluntary contraction. The duration of the CSP was used to as
sess the level of intracortical inhibition in patients with untreated idiop
athic generalized epilepsy (IGE). Mean CSP duration was assessed at three T
MS stimuli in 21 patients with IGE compared with 19 normal control subjects
. Mean CSP duration was increased at all stimulus intensities, indicating t
hat intracortical inhibition is increased in patients with IGE.