The paper is devoted to the study of the so-called sequential normal compac
tness conditions in variational analysis in infinite-dimensional spaces. Su
ch conditions are needed for many aspects of generalized differentiation, p
articularly for calculus rules involving normal cones to sets, sub differen
tials of nonsmooth functions, and coderivatives of set-valued mappings. The
se conditions automatically hold in finite-dimensional spaces and reveal on
e of the most principal differences between finite-dimensional and infinite
-dimensional variational theories. However, up to now it was not investigat
ed how such conditions behave under various operations with sets, functions
, and multifunctions. In this paper we address these questions and present
new results that establish an efficient calculus of sequential normal compa
ctness in a fairly general setting.