Kh. Shaughnessy et Rs. Booth, Sterically demanding, water-soluble alkylphosphines as ligands for high activity Suzuki coupling of aryl bromides in aqueous solvents, ORG LETT, 3(17), 2001, pp. 2757-2759
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Sterically demanding, water-soluble alkylphosphines have been found to give
highly active catalysts for Suzuki coupling of aryl bromides in aqueous so
lvents. A variety of aryl bromides and boronic acids were coupled in excell
ent yield. Turnover numbers up to 734 000 mmol/mmol Pd have been achieved u
nder mild conditions.