Transfer hydrogenation of carbonyl compounds catalyzed by a ruthenium-acetamido complex: Evidence for a stepwise hydrogen transfer mechanism

Authors
Yi, CS He, ZJ Guzei, IA
Citation
Cs. Yi et al., Transfer hydrogenation of carbonyl compounds catalyzed by a ruthenium-acetamido complex: Evidence for a stepwise hydrogen transfer mechanism, ORGANOMETAL, 20(17), 2001, pp. 3641-3643
Citations number
42
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANOMETALLICS
ISSN journal
02767333 → ACNP
Volume
20
Issue
17
Year of publication
2001
Pages
3641 - 3643
Database
ISI
SICI code
0276-7333(20010820)20:17<3641:THOCCC>2.0.ZU;2-H
Abstract
The ruthenium-acetamido complex, prepared from the reaction of [(PCy3)(2)(C O)(CH3CN)(2)RuH](+)-BF4- with KOH in 2-propanol, was found to be an effecti ve catalyst for the transfer hydrogenation of carbonyl compounds and imines . Observation of both the inverse deuterium isotope effect and the competit ive inhibition by added phosphine provided strong evidence for a stepwise m echanism of proton and hydride transfer via a coordinatively unsaturated ru thenium-amido species.