Effect of global system for mobile communication (GSM)-like radiofrequencyfields on vascular permeability in mouse brain

The effect of global system for mobile communication (GSM) radiofrequency f ields on vascular permeability In the brain was studied using a purpose-des igned exposure system at 898.4 MHz. Mice (n = 30) were given a single far f ield, whole body exposure for 60 minutes at a specific absorption rate of 4 W/kg. Control mice were also sham-exposed (n = 10) or permitted free movem ent in a cage (n = 10) to exclude any stress-related effects. Vascular perm eability changes were detected using albumin immunohistochemistry and the e fficacy of this vascular tracer was confirmed with a positive control group exposed to a clostridial toxin known to increase vascular permeability in the brain. No significant difference in albumin extravasation was detected between any of the groups at the light microscope level using the albumin m arker.