Cytotoxic cyclopenta[b]benzofuran derivatives from the stem bark of Aglaiaformosana

Authors
Wang, SK Duh, CY
Citation
Sk. Wang et Cy. Duh, Cytotoxic cyclopenta[b]benzofuran derivatives from the stem bark of Aglaiaformosana, PLANTA MED, 67(6), 2001, pp. 555-557
Citations number
9
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
00320943 → ACNP
Volume
67
Issue
6
Year of publication
2001
Pages
555 - 557
Database
ISI
SICI code
0032-0943(200108)67:6<555:CCDFTS>2.0.ZU;2-O
Abstract
A new cytotoxic cyclopenta[b]benzofuran derivative, aglaiformosanin (1) and three known cyclopenta[b]benzofuran derivatives (2-4) were isolated from t he stem bark of Aglaia formosana. Compounds 1-4 exhibited potent cytotoxici ty against the P-388, KB, HT-29, HL-60, and A549 cell lines. The structure of compound I was determined by spectroscopic analysis.