This paper uses a 'knowledge-based' approach to compare the management of R
&D in two leading chemicals companies, one British (ICI plc) and one Japane
se. It describes key differences in the ways they integrate the 'near-marke
t' knowledge of business units and the scientific knowledge and technical e
xpertise of R&D personnel in central R&D facilities. It shows that the same
management practices that underpin superior 'integrative capabilities' in
the Japanese firm, including central funding of R&D, job-rotation and caree
r structures and multidisciplinary project teams, also result in significan
t R&D weaknesses. The comparison demonstrates that different organisational
mechanisms are needed to support (1) the development and (2) the leveragin
g of specialist knowledge within different innovation contexts. Firms must
be able to strike a balance between integrative and specialist capabilities
to get the most from their R&D. Moreover, the above characteristics which
underpin these capabilities are often 'embedded' in the broader organisatio
n making them difficult to emulate when they represent 'best-practice' but
also making them difficult to change in response to new threats and opportu
nities.