X-ray fluorescence, using Cu K alpha and K beta radiation, has been used to
measure the Fe content of skin of two groups of rats, one Fe overloaded an
d one control group. These skin Fe levels were compared to the liver and he
art Fe levels measured using colorimetry. Correlation coefficients of 0.86
and 0.88 respectively were found indicating that skin Fe levels may be a po
tential marker for body iron burden. (C) 2001 Elsevier Science Ltd. All rig
hts reserved.