A fast spin-echo sequence weighted with a time constant that defines the ma
gnetic relaxation of spins under the influence of a radio-frequency field (
T1(rho)) was used in six subjects to measure magnetic resonance (MR) relaxa
tion times in the knee joint with a 1.5-T MR imager. A quantitative compari
son of T2- and T1(rho)-weighted MR images was also performed. Substantial T
1(rho) dispersion was demonstrated in human articular cartilage, but muscle
did not demonstrate much dispersion. Tl-rho-weighted images depicted a cho
ndral lesion with 25% better signal-difference-to-noise ratios than compara
ble T2-weighted images. This technique may depict cartilage and muscular ab
normalities.