Kinetics of the conformer reactions: II. Significance of media in the electrophilic addition reactions

The kinetics of electrophilic addition reaction of bromine to a multiple bo nd in a series of conformationally unhomogenous 2-substituted 1,3-dioxa-5-c ycloheptenes was studied. We found that the compounds with trans structure are formed. The partial reaction rate constant for chair and twist forms an d the reaction susceptibility parameters to the substituent electronic effe ct at the C-2 atom are obtained. Relative reactivity of the alternative ste ric structures is defined by the specific solvation of the substrate. The r esult obtained are compared with those achieved without accounting for conf ormational term.