Bartonella henselae serostatus is not correlated with neurocognitive decline in HIV infection

Authors
Wallace, MR Persing, DH McCutchan, JA Magara, J Nelson, JA Heaton, RK Tasker, SA Grant, I
Citation
Mr. Wallace et al., Bartonella henselae serostatus is not correlated with neurocognitive decline in HIV infection, SC J IN DIS, 33(8), 2001, pp. 593-595
Citations number
21
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
ISSN journal
00365548 → ACNP
Volume
33
Issue
8
Year of publication
2001
Pages
593 - 595
Database
ISI
SICI code
0036-5548(2001)33:8<593:BHSINC>2.0.ZU;2-0
Abstract
Bartonella henselae has been implicated as a significant cause of HIV-assoc iated dementia. We attempted to confirm this association by utilizing the d atabase of the San Diego HIV Neurobehavioral Research Center, which collect s longitudinal neurocognitive and laboratory data on over 500 HIV-infected participants. Utilizing an immunofluorescent assay we found that 11% of 177 subjects, half of whom had documented neurocognitive decline, were seropos itive for B. hensalae. There was no correlation between B. hensalae seropos itivity and neurocognitive decline. The role of B. hensalae in HIV-associat ed dementia remains ambiguous.