A novel bridged stilbenoid trimer and four highly condensed stilbenoid oligomers in Vatica rassak

Authors
Ito, T Tanaka, T Nakaya, K Iinuma, M Takahashi, Y Naganawa, H Ohyama, M Nakanishi, Y Bastow, KF Lee, KH
Citation
T. Ito et al., A novel bridged stilbenoid trimer and four highly condensed stilbenoid oligomers in Vatica rassak, TETRAHEDRON, 57(34), 2001, pp. 7309-7321
Citations number
48
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
34
Year of publication
2001
Pages
7309 - 7321
Database
ISI
SICI code
0040-4020(20010820)57:34<7309:ANBSTA>2.0.ZU;2-3
Abstract
Vaticanol G (1) and vaticaside D (2) isolated from stem bark of Vatica rass ak (Dipterocarpaceae) were the first instance of stilbenoid trimers with an unusual tribenzobicyclo[3.3.2]decatriene system. Vaticanols D (3) and H (4 )-J (6) were elucidated to be a stilbenoid hexamer or heptamer containing a structurally identical trimeric unit. Their structures and the relative co nfigurations were established on the basis of 2D NMR spectroscopy. The hexa mers (3, 4 and 5) and the heptemer (6) showed cytotoxicity against KB cells . (C) 2001 Elsevier Science Ltd. All rights reserved.