Organophosphorus chemistry of fullerene: synthesis and biological effects of organophosphorus compounds of C-60

Authors
Cheng, FY Yang, XL Fan, CH Zhu, HS
Citation
Fy. Cheng et al., Organophosphorus chemistry of fullerene: synthesis and biological effects of organophosphorus compounds of C-60, TETRAHEDRON, 57(34), 2001, pp. 7331-7335
Citations number
19
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
34
Year of publication
2001
Pages
7331 - 7335
Database
ISI
SICI code
0040-4020(20010820)57:34<7331:OCOFSA>2.0.ZU;2-B
Abstract
Synthesis of novel methanophosphonate and methanophosphonic acid C-60 deriv atives was achieved, and their cytotoxicity was studied. In particular, a b is-methanophosphonate C-60 derivative displayed photo-induced cytotoxicity on HeLa cells with IC50 value of 1.30 muM. (C) 2001 Elsevier Science Ltd. A ll rights reserved.