Synthesis of C-3 alkyl analogs of cocaine

Authors
Deng, SM Huang, DW Landry, DW
Citation
Sm. Deng et al., Synthesis of C-3 alkyl analogs of cocaine, TETRAHEDR L, 42(36), 2001, pp. 6259-6261
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
36
Year of publication
2001
Pages
6259 - 6261
Database
ISI
SICI code
0040-4039(20010903)42:36<6259:SOCAAO>2.0.ZU;2-I
Abstract
The first general stereocontrolled approach to C-3 alkyl analogs of cocaine is described. The route utilized versatile intermediates 2 beta -hydroxyme thyl-3 alpha -cyanotropane and 2 beta -hydroxymethyl-3 beta -cyanotropane. (C) 2001 Elsevier Science Ltd. All rights reserved.