Enantioselective Michael reaction of malonates and chalcones by phase-transfer catalysis using chiral quaternary ammonium salt

Authors
Kim, DY Huh, SC Kim, SM
Citation
Dy. Kim et al., Enantioselective Michael reaction of malonates and chalcones by phase-transfer catalysis using chiral quaternary ammonium salt, TETRAHEDR L, 42(36), 2001, pp. 6299-6301
Citations number
43
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
36
Year of publication
2001
Pages
6299 - 6301
Database
ISI
SICI code
0040-4039(20010903)42:36<6299:EMROMA>2.0.ZU;2-#
Abstract
The catalytic enantioselective Michael reaction promoted by quaternary ammo nium salt from cinchonidine as a phase-transfer catalyst is described. Trea tment of malonate with chalcone derivatives under mild reaction conditions afforded the corresponding Michael adducts in good yields with good to mode rate enantiomeric excesses. (C) 2001 Elsevier Science Ltd. All rights reser ved.