Chiral alpha,omega-diaminoethers derived from D-mannitol and L-treitol as building blocks for the synthesis of macrocyclic compounds possessing 1,3-benzenedicarboxamide or 2,6-pyridinedicarboxamide subunits
P. Piatek et al., Chiral alpha,omega-diaminoethers derived from D-mannitol and L-treitol as building blocks for the synthesis of macrocyclic compounds possessing 1,3-benzenedicarboxamide or 2,6-pyridinedicarboxamide subunits, TETRAHEDR-A, 12(12), 2001, pp. 1763-1769
Three new chiral alpha,omega -diaminoethers, derivatives Of D-mannitol and
L-treitol, possessing C-2 symmetry are prepared. The alpha,omega -diaminoet
hers were applied to the macrocyclization reaction under non-high-dilution
conditions, which afforded chiral macrocyclic diamides possessing either 2,
6-pyridinedicarboxamide or 1,3-benzenedicarboxamide moieties. (C) 2001 Else
vier Science Ltd. All rights reserved.