Paramecium genome survey: a pilot project

Authors
Dessen, P Zagulski, M Gromadka, R Plattner, H Kissmehl, R Meyer, E Betermier, M Schultz, JE Linder, JU Pearlman, RE Kung, C Forney, J Satir, BH Van Houten, JL Keller, AM Froissard, M Sperling, L Cohen, J
Citation
P. Dessen et al., Paramecium genome survey: a pilot project, TRENDS GEN, 17(6), 2001, pp. 306-308
Citations number
27
Categorie Soggetti
Molecular Biology & Genetics
Journal title
TRENDS IN GENETICS
ISSN journal
01689525 → ACNP
Volume
17
Issue
6
Year of publication
2001
Pages
306 - 308
Database
ISI
SICI code
0168-9525(200106)17:6<306:PGSAPP>2.0.ZU;2-6
Abstract
A consortium of laboratories undertook a pilot sequencing project to gain i nsight into the genome of Paramecium. Plasmid-end sequencing of DNA fragmen ts from the somatic nucleus together with similarity searches identified 72 2 potential protein-coding genes. High gene density and uniform small intro n size make random sequencing of somatic chromosomes a cost-effective strat egy for gene discovery in this organism.