This paper discusses the rational exploitation of main resources and preven
tion of geohazards in karst regions. There exist relationship chains betwee
n natural disasters in the earth, which include the chain between geologica
l hazards and climatic hazards, the chain between geological hazards and bi
ogenic hazards as well as the one between geological hazards. Irrational ex
ploitation of all resources will inevitably cause hazards. Therefore it is
very important to discuss the problem related to prevention of geohazards b
y rational exploitation of resources.