The precautionary principle has provoked a spirited debate among environmen
talists worldwide, but it is equally relevant to public health and shares m
uch with primary prevention. Its central components are (1) taking preventi
ve action in the face of uncertainty; (2) shifting the burden of proof to t
he proponents of an activity; (3) exploring a wide range of alternatives to
possibly harmful actions; and (4) increasing public participation in decis
ion making, Precaution is relevant to public health, because it can help to
prevent unintended consequences of well-intentioned public health interven
tions by ensuring a more thorough assessment of the problems and proposed s
olutions. It can also be a positive force for change. Three aspects are str
essed: promoting the search for safer technologies, encouraging greater dem
ocracy and openness in public health policy, and stimulating reevaluation o
f the methods of public health science.