Granulocyte transfusion in the management of fulminant invasive fungal rhinosinusitis

Usually, fulminant, invasive fungal rhinosinusitis is observed in the immun ocompromised patient and is associated with significant morbidity and morta lity. A high index of suspicion and early diagnosis is imperative for optim izing outcome. Mainstays of treatment include antifungal agents and radical resection of necrotic tissue. Reversal of the underlying medical condition , when possible, is a critical part of the management. In the neutropenic p opulation, granulocyte transfusion may represent an adjunct to current ther apy. We Provide the first report of a case of invasive fungal rhinosinusiti s in which this intervention was used.