A novel 1 : 1 complex of potassium mikanin-3-O-sulfate with methanol

Citation
Rw. Jiang et al., A novel 1 : 1 complex of potassium mikanin-3-O-sulfate with methanol, CHEM PHARM, 49(9), 2001, pp. 1166-1169
Citations number
14
Categorie Soggetti
Chemistry & Analysis
Journal title
CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN journal
00092363 → ACNP
Volume
49
Issue
9
Year of publication
2001
Pages
1166 - 1169
Database
ISI
SICI code
0009-2363(200109)49:9<1166:AN1:1C>2.0.ZU;2-Y
Abstract
Mikanin-3-O-sulfate (1), in the form of its potassium salt, together with m ikanin (2) and alpinetin (3) were isolated from Mikania micrantha. The crys tal structures of K(1). CH3OH, 2 and 3 .H2O were established by Xray crysta llography. The potassium ions in K(1). CH3OH are bridged by O5, O7 and O8 t o form a chain of face-sharing KO8 coordination polyhedra, from which the a glycon units are outstretched to form a polymeric molecular column. Adjacen t molecular columns are linked by pi-pi stacking between parallel, intercal ating aglycon units to form layers matching the (10 (1) over bar) family of planes, which are further interconnected into a three-dimensional supramol ecular assembly. Sulfation at 3-OH induced better co-planarity and conjugat ion of the rings.