From the aqueous-ethanolic antipsoriatic mahonia extract a mixture of low-m
olecular-mass polysaccharides was isolated by ethanol precipitation of the
undialyzable portion. They were composed of neutral sugar components with d
ominating glucose. Ion-exchange and gel-permeation chromatography was emplo
yed to obtain the dominant polysaccharide component which was proved by met
hylation analysis and NMR spectrometric measurements to be a linear (1 -->4
)-beta -D-glucan.