Separation of products of thebaine rearrangement by capillary electrophoresis in the presence of cyclodextrins

Authors
Proksa, B
Citation
B. Proksa, Separation of products of thebaine rearrangement by capillary electrophoresis in the presence of cyclodextrins, CHEM PAP-CH, 55(3), 2001, pp. 196-201
Citations number
19
Categorie Soggetti
Chemistry
Journal title
CHEMICAL PAPERS-CHEMICKE ZVESTI
ISSN journal
03666352 → ACNP
Volume
55
Issue
3
Year of publication
2001
Pages
196 - 201
Database
ISI
SICI code
0366-6352(2001)55:3<196:SOPOTR>2.0.ZU;2-W
Abstract
Separation of thebaine and products of its oxidation (14-hydroxycodeinone, 14-hydroxycodeinone N-oxide, (10S)-hydroxythebaine, (8S)-hydroxyoxycodone) as well as rearrangement in acidic media (thebenine, morphothebaine) was st udied by capillary zone electrophoresis in the presence of modified cyclode xtrins. Conditions for separation of thebaine/10-hydroxythebaine were compa red with those of morphine/10-hydroxymorphine and codeine/ 10-hydroxycodein e.