Spectroturbidimetry of liposome suspensions

Citation
Ng. Khlebtsov et al., Spectroturbidimetry of liposome suspensions, COLL J, 63(4), 2001, pp. 491-498
Citations number
24
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
COLLOID JOURNAL
ISSN journal
1061933X → ACNP
Volume
63
Issue
4
Year of publication
2001
Pages
491 - 498
Database
ISI
SICI code
1061-933X(200107/08)63:4<491:SOLS>2.0.ZU;2-X
Abstract
Spectroturbidimetric method of the determination of the average size and th ickness of the shell in polydisperse suspensions of liposome particles was discussed. The method is based on measuring the wave exponent of suspension (the logarithmic slope of turbidity spectrum) and specific turbidity (turb idity per unit mass concentration of dispersed substance). The solution of inverse problem was performed using the exact calculation of the characteri stics of light scattering for polydisperse spherical bilayer particles with allowance for spectral dependence of optical constants. Practical realizat ion of this method is illustrated by the experimental determinations of the structural parameters of liposomes prepared from egg lecithin.