After the 1999 outbreak of West Nile (WN) encephalitis in New York horses,
a case definition was developed that specified the clinical signs, coupled
with laboratory test results, required to classify cases of WN encephalitis
in equines as either probable or confirmed. In 2000, 60 horses from seven
states met the criteria for a confirmed case. The cumulative experience fro
m clinical observations and diagnostic testing during the 1999 and 2000 out
breaks of WN encephalitis in horses will contribute to further refinement o
f diagnostic criteria.