Adenosquamous carcinoma of the pancreas - Successful treatment with extended radical surgery, intraoperative radiation therapy, and locoregional chemotherapy

Background. Adenosquamous carcinoma of the pancreas is a rare tumor with an extremely poor survival rate. No obvious evidence that multidisciplinary t reatments improves the prognosis and survival has been reported. Patient and Results. A 63-yr-old female with adenosquamous carcinoma of the pancreas underwent extended radical surgery, intraoperative radiation ther apy, postoperative intraarterial chemotherapy, and external beam radiation therapy. The patient is alive at 40 mo after surgery with no recurrence. Conclusions. Multidisciplinary treatments including aggressive surgery, int raoperative radiation therapy, and locoregional chemotherapy might improve the survival of patients with adenosquamous carcinoma of the pancreas to in hibit liver metastasis and local recurrence.