Abp1p and cortactin, new "hand-holds" for actin

Recently, two new ligands of the Arp2/3 complex have been described that ma y shed light on the way cells organize complex networks of actin in respons e to signals. Abp1p, a yeast protein involved in endocytosis, and cortactin , a mammalian sic substrate, both enhance the ability of the Arp2/3 complex to assemble branched actin filament networks.