A tracking algorithm has been developed to efficiently track a moving objec
t in two-dimensional image space. The algorithm employs a limited exhaustiv
e template matching scheme that combines the accuracy of an exhaustive sear
ch with the computational efficiency of a coarse-fine template matching sch
eme, The overall result is an accurate, time-efficient tracking algorithm.
After providing a theoretical discussion of the algorithm, three separate b
iomedical applications of the algorithm are described. (1) stabilizing an i
rradiating laser on the retinal surface for photocoagulation treatment, (2)
measuring target fixation eye movement to construct pattern densities at t
he retina, and (3) tracking a rat swimming in a Morris Water Maze for psych
ophysiological studies. Results for each application is provided, The paper
concludes Vith a discussion of the relative merits of the tracking algorit
hm and recommendations for methods to improve the performance of the algori
thm. (C) 2001 SPIE and IS&T.