Purpose: We have used an extra-anatomic subcutaneous alloplastic ureteral r
eplacement initially to bypass ureteral obstruction secondary to advanced p
elvic malignancies in patients with a short life expectancy. Following the
encouraging preliminary results, our list of indications has broadened to i
nclude complex benign ureteral strictures. We herein report the long-term o
utcome.
Patients and Methods: A series of 35 subcutaneous prosthetic ureters were i
mplanted percutaneously in 27 patients (19 unilateral and 8 bilateral) to b
ypass extrinsic ureteral obstructions. The nature of obstruction was neopla
stic in 22 patients and benign in 5. A composite prosthesis, consisting of
two coaxial tubes-internal pure smooth silicone covered by coiled e-PTFE-ha
s been designed to serve as the ureteral replacement. This tube is inserted
percutaneously into the renal pelvis, tunnelled subcutaneously, and introd
uced through a small suprapubic incision in the bladder. All patients were
followed to date or until death from tumor. The mean follow-up was 6.3 mont
hs for the deceased patients and 47 months for the surviving ones, the long
est follow-up being 84 months.
Results: No operative or immediate postoperative deaths were observed. Init
ial difficulty in placing the prosthesis was encountered in 5 of the 27 pat
ients (19%). Secondary parietal complications occurred in 8.5% of cases (3/
35). The prosthetic ureter had to be removed in one patient because of skin
erosion. Return to a standard percutaneous nephrostomy was needed in two p
atients because of local tumor progression with bladder fistulae. Five pati
ents are alive with the prosthesis in place and a follow-up as long as 84 m
onths without encrustation, infection, obstruction, or skin problems and wi
th normally functioning kidneys.
Conclusion: The subcutaneous urinary diversion using a silicone-PTFE prosth
esis is an efficient and minimally invasive way to bypass malignant or comp
lex benign obstructions of the ureters that otherwise would necessitate per
manent nephrostomy drainage.