The erosive potentials of a number of commercially available artificial sal
iva substitutes have been investigated using an in vitro hydroxyapatite pow
der dissolution assay. Most of the saliva substitutes examined did not show
any appreciable erosive potential, although one product resulted in greate
r mineral dissolution levels. There appeared to be little correlation betwe
en pH and mineral dissolution levels for the different saliva substitutes e
xamined. Whilst saliva substitutes may be of assistance in maintaining some
physiological function in patients with impaired salivary flow, it is impo
rtant to choose a product with low erosive potential where the natural dent
ition is present.