Resorption of the temporomandibular condylar bone according to subtypes ofjuvenile chronic arthritis

Citation
Tk. Pedersen et al., Resorption of the temporomandibular condylar bone according to subtypes ofjuvenile chronic arthritis, J RHEUMATOL, 28(9), 2001, pp. 2109-2115
Citations number
37
Categorie Soggetti
Rheumatology,"da verificare
Journal title
JOURNAL OF RHEUMATOLOGY
ISSN journal
0315162X → ACNP
Volume
28
Issue
9
Year of publication
2001
Pages
2109 - 2115
Database
ISI
SICI code
0315-162X(200109)28:9<2109:ROTTCB>2.0.ZU;2-V
Abstract
Objective. To evaluate the relative impact of sex, type of onset, course of disease. age at onset, duration of disease and status of HLA-B27, antinucl ear antibodies (ANA), and rheumatoid factor on the risk of developing a con dylar erosion. Methods. Condylar changes of the temporomandibular joint (TMJ) were diagnos ed on orthopantomograms from 169 consecutive patients with juvenile chronic arthritis (JCA). A multiple regression analysis was applied to establish t he relative weight of the independent variables affecting the severity of t he condylar erosion. Results. It was found that 62.1% of the patients exhibited condylar resorpt ion. The highest prevalence was seen in children with a polyarticular onset or course of disease and early age at onset and severe resorption was also frequent in these groups. Patients with positive ANA also had a high preva lence but with a mild degree of resorption. In contrast, HLA-B27 positive p atients had a lower risk of TMJ involvement and resorptive changes of the c ondyle. Conclusion. Polyarticular and early onset arthritis are associated with a h igh risk for TMJ involvement and a severe condylar bone loss can be expecte d. ANA positive patients have a high prevalence. and B27 positive patients have a low prevalence of TMJ arthritis but in both subgroups, the outcome o f the bone resorptive process is mild.