Poor longterm success has been reported for penile vein ligation the l
ast few years. Therefore, we decided to re-investigate our group of 14
7 patients who were operated on between 1987 and 1996. All patients sh
owed a negative response to intracavernous injection therapy at the ti
me of diagnosis and revealed a maintenance flow > 15 ml/min, as well a
s a pathological venous flow with pharmacocavernosometry or pharmacoca
vernosography. These patients underwent ligation of all superficial do
rsal veins and resection of the deep dorsal vein of the penis. An up-t
o-date record of the success of the operation was kept either by a ren
ewed clinical visit or by a standardized telephone interview or questi
onnaire. A total of 126 patients were available here for long-term fol
low-up. We divided the findings into three groups: complete spontaneou
s erection, postoperative response to cavernous autoinjection therapy
and no changes in erectile competency postoperatively. The short-term
success rate for these groups after 1-3 months was an outcome of 31 (2
4.6 %), 25 (19.8 %) and 70 (55.6 %) patients; 86 % of the cases whose
results deteriorated after the initial operation success rate had this
happen within the first postoperative year (p less than or equal to 0
.001). Favorable prognostic factors were preoperative erectile dysfunc
tion of less than or equal to 7 years, a normal CC-EMG and a maintenan
ce flow of less than or equal to 45 ml/min. If all three parameters we
re present, the long-term success rate (spontaneous erection plus resp
onse to intracavernous injection) of 30% of all patients was found to
rise to 67 % in this selected group of patients (p less than or equal
to 0.001). This study reveals that long-term success for unselected pa
tients undergoing penile venous surgery is disappointing; however, car
eful selection of patients by certain prognostic factors can improve l
ong-term results.